Stem cells

A stem cell characterizes by its capability for self-renewal and differentiation into cells of various lineages. Mesenchymal stem cells (MSCs). also known as pluripotent stromal mesenchymal cells, are a heterogeneous cell population that in vitro proliferate attached to plastic. With a morphology quite similar to fibroblasts, they can form colonies in vitro and differentiate into cells of mesodermal lineage, such as osteocytes, chondrocytes and adipocytes, as well as into cells of other embryo lineages. MSCs in adults can be obtained from various sources i.e. skeletal muscle, adipose tissue, bone marrow, or uterine cervix. Phenotypic characterization of MSCs involve biological markers such as cell surface receptors.